Cadmium Contamination in Soil and Water and Its Impact on Human Health in Southeast Asia: A Systematic Review
DOI:
https://doi.org/10.37287/ijghr.v8i1.1672Keywords:
cadmium exposure, environmental health, heavy metals, soil and water pollution, southeast asiaAbstract
This Cadmium (Cd) is a highly toxic heavy metal that poses serious threats to environmental and human health, especially in Southeast Asia, where industrial, mining, and agricultural activities are rapidly increasing. Chronic exposure to cadmium can lead to kidney damage, bone disorders, reproductive issues, and cancer, especially in areas relying on local water and food sources. This study employed a systematic literature review method, analyzing relevant studies published from databases including PubMed, Scopus, Google Scholar, and ScienceDirect. Keywords used included "cadmium contamination", "soil pollution", "water pollution", and "Southeast Asia". Inclusion criteria focused on studies reporting cadmium levels in soil or water and their health impacts in Southeast Asia. Cadmium contamination was reported in multiple countries, particularly in Thailand, Indonesia, and Vietnam. The primary sources of pollution include mining, fertilizer use, and industrial discharge. In many cases, cadmium levels in soil and water exceeded safety limits set by WHO and national standards and Health impacts. Cadmium contamination in Southeast Asia is a critical environmental and public health issue. Consistent findings across studies highlight the need for better waste management, stricter regulations, and regular monitoring. Public awareness and targeted interventions are essential to mitigate exposure and protect vulnerable populations.
References
Ahmad, W., Alharthy, R. D., Zubair, M., Ahmed, M., Hameed, A. dan Rafique, S. (2023) 'Assessment of heavy and toxic metal contamination in soil and water for human health risk evaluation', Environmental Monitoring and Assessment. https://doi.org/10.1038/s41598-021-94616-4
Ahmed, M. F. dan Mokhtar, M. B. (2020) 'Assessing Cadmium and Chromium Concentrations in Drinking Water to Predict Health Risk in Malaysia', International Journal of Environmental Research and Public Health, vol. 17, no. 8, pp. 2966. https://doi.org/10.3390/ijerph17082966
Annar, S. (2022). The characteristics, toxicity and effects of heavy metals arsenic, mercury and cadmium: A review. Int. J. Multidiscip. Educ. Res, 11, 35-43.
Anggraeni, D. et al. (2024) 'Analysis of heavy metals (Pb and Cd) in soil layers of Indonesia: Spatial distribution, potential source, and groundwater effect', Case Studies in Chemical and Environmental Engineering, vol. 9, p. 100652. . https://doi.org/10.1016/j.cscee.2024.100652
BEUP, R. A. et al. (2024) 'Assessing the levels of heavy metals Cd, Cr, and Pb in the naturally occurring red seaweed Gracilariopsis heteroclada in Iloilo Province, Philippines, for potential mass cultivation', Nusantara Bioscience, vol. 16, no. 2. https://doi.org/10.13057/nusbiosci/n160201
Bhakta, J. dan Munekage, Y. (2010) 'Spatial Distribution and Contamination Status of Arsenic, Cadmium and Lead in some Coastal Shrimp (Macrobrachium rosenbergii) Farming Ponds of Viet Nam', Pacific Journal of Science and Technology, vol. 11.
Bobon-Carnice, P. A., Varona, M. B. dan Amistoso, J.-A. L. (2022) 'CADMIUM, NICKEL, AND LEAD CONCENTRATION OF MUNICIPAL DUMPSITE IN WESTERN SAMAR, PHILIPPINES', BIOTROPIA, vol. 29, no. 3. https://doi.org/10.11598/btb.2022.29.3.1669
Boonprasert, K. et al. (2011) 'Urinary and blood cadmium levels in relation to types of food and water intake and smoking status in a Thai population residing in cadmium-contaminated areas in Mae Sot', The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 42, no. 6, pp. 1521–1530.
Bouida, L. et al. (2022) 'A review on cadmium and lead contamination: Sources, fate, mechanisms, health impacts and remediation methods', Toxics, vol. 10, no. 2, p. 59. https://doi.org/10.3390/toxics10020059
Briffa, J., Sinagra, E., & Blundell, R. (2020). Heavy metal pollution in the environment and their toxicological effects on humans. Heliyon, 6(9).
Chanpiwat, P. dan Sthiannopkao, S. (2014) 'Status of metal levels and their potential sources of contamination in Southeast Asian rivers', Environmental Science and Pollution Research, vol. 21, pp. 220–233. https://doi.org/10.1007/s11356-013-1858-8
Charkiewicz, A. E. et al. (2023) 'Cadmium toxicity and health effects—a brief summary', Molecules, vol. 28, no. 18, p. 6620. https://doi.org/10.3390/molecules28186620
Chheang, L. et al. (2021) 'Heavy metal contamination and human health implications in the Chan Thnal reservoir, Cambodia', Sustainability, vol. 13, no. 24, p. 13538. https://doi.org/10.3390/su132413538
Decharat, S. dan Pan-In, P. (2020) 'Risk Assessment of Lead and Cadmium in Drinking Water for School use in Nakhon Si Thammarat Province, Thailand', Environmental Analysis, Health and Toxicology, vol. 35, no. 1, p. e2020002. https://doi.org/10.5620/eaht.e2020002
Elgawish, R. A. dan Abdelrazek, H. M. A. (2014) 'Effects of lead acetate on testicular function and caspase-3 expression with respect to the protective effect of cinnamon in albino rats', Toxicology Reports, vol. 1, pp. 795–801.
Fatmasari, D., Wahyuni, A. dan Sari, N. P. (2023) 'Hubungan paparan timbal (Pb) dan kadmium (Cd) terhadap kualitas sperma pria usia produktif di daerah industri', Jurnal Kesehatan Lingkungan Indonesia, vol. 22, no. 1, pp. 45–53.
Ganeshamurthy, A. N., Ravisankar, N. dan Ramesh, K. (2008) 'Soil pollution and its impact on agriculture and environment', Proceedings of National Seminar on Environmental Pollution and Management, Tamil Nadu, India.
Genchi, G. et al. (2020) 'Toxic effects of cadmium: Cellular and molecular impact on human health', International Journal of Environmental Research and Public Health, vol. 17, no. 11, p. 3782. https://doi.org/10.3390/ijerph17113782
Georgakopoulou, V. E., Spandidos, D. A., & Corlateanu, A. (2025). Diagnostic tools in respiratory medicine. Biomedical Reports, 23(1), 112.
Goh, T. A., Ramchunder, S. J. dan Ziegler, A. D. (2022) 'Low presence of potentially toxic elements in Singapore urban garden soils', CABI Agriculture and Bioscience, vol. 3, p. 60. https://doi.org/10.1186/s43170-022-00126-2
Hardiyanto, H. dan De Guzman, C. C. (2008) 'Identification of lead and cadmium levels in white cabbage (Brassica rapa L.), soil, and irrigation water of urban agricultural sites in the Philippines', Indonesian Journal of Agricultural Science, vol. 9, no. 1, pp. 1–6. https://repository.pertanian.go.id/handle/123456789/97
Huang, Y., Mubeen, S., Yang, Z., & Wang, J. (2022). Cadmium contamination in agricultural soils and crops. In Theories and Methods for Minimizing Cadmium Pollution in Crops: Case Studies on Water Spinach (pp. 1-30). Singapore: Springer Nature Singapore.
Hughes, M. F. (2002) 'Arsenic toxicity and potential mechanisms of action', Toxicology Letters, vol. 133, no. 1, pp. 1–16. https://doi.org/10.1016/S0378-4274(02)00084-X.
Ilieva, I., Sainova, I., & Yosifcheva, K. (2020). Toxic effects of heavy metals (lead and cadmium) on sperm quality and male fertility. Acta morphol. anthropol, 27(3-4).
Jiraungkoorskul, K. et al. (2016) 'Cadmium contamination in farmland soil and water near zinc mining site', Kesmas, vol. 10, no. 3, pp. 99–103. https://doi.org/10.21109/kesmas.v10i3.945
Jurasovic, J. et al. (2004) 'Seminal plasma zinc and copper in relation to semen quality', Reproductive Toxicology, vol. 19, no. 3, pp. 353–361.
Komarnicki, G. J. K. (2005) 'Lead and cadmium in indoor air and the urban environment', Environmental Pollution, vol. 136, pp. 47–61.
Krissanakriangkrai, O. et al. (2015) 'Bioavailable Cadmium in Water, Sediment, and Fish, in a Highly Contaminated Area on the Thai-Myanmar Border', Science & Technology Asia, vol. 14, no. 4, pp. 60–68. https://ph02.tci-thaijo.org/index.php/SciTechAsia/article/view/41347
Kyi Pyar Zin, L. H. Lim, J. M. R. Sarath Bandara, H. M. Thippeswamy (2017) 'Heavy Metals in Paddy Soils of Brunei Darussalam and Their Relationship with Selected Soil Properties', International Journal of Environmental Monitoring and Analysis, vol. 5, no. 3, pp. 64–72. https://doi.org/10.11648/j.ijema.20170503.11
Lanphear, B. P. et al. (2005) 'Low-level environmental lead exposure and children's intellectual function: an international pooled analysis', Environmental Health Perspectives, vol. 113, no. 7, pp. 894–899.
Needleman, H. L. et al. (1979) 'Deficits in psychologic and classroom performance of children with elevated dentine lead levels', New England Journal of Medicine, vol. 300, no. 13, pp. 689–695.
Ngoc, N. T. M. et al. (2020) 'Chromium, Cadmium, Lead, and Arsenic Concentrations in Water, Vegetables, and Seafood Consumed in a Coastal Area in Northern Vietnam', Environmental Health Insights, vol. 14, 1178630220921410. https://doi.org/10.1177/1178630220921410
Nguyen, T. T., Tran, T. A. dan Van, H. T. (2019) 'Assessment of heavy metal contamination in soil and groundwater in industrial zones in Ho Chi Minh City, Vietnam', Environmental Monitoring and Assessment, vol. 191, no. 11, p. 654. https://doi.org/10.1007/s10661-019-7855-1
Kuna, G., Gullipalli, S., & Chintada, V. (2024). Health risks associated with cadmium toxicity. In Cadmium Toxicity in Water: Challenges and Solutions (pp. 47-60). Cham: Springer Nature Switzerland.
Pandiangan, F. I. dan Audah, K. A. (2022) 'Heavy metal contamination status in the soil-water-rice system near coal-fired power plants in Cilacap, Indonesia', Jurnal Ilmiah Pertanian, vol. 19, no. 3, pp. 145–154. https://doi.org/10.31849/jip.v19i3.10568
Peana, M. et al. (2022) 'Biological effects of human exposure to environmental cadmium', Biomolecules, vol. 13, p. 36.
Pogrmic-Majkic, K. et al. (2021) 'Structural and functional ovarian disorders caused by cadmium: In vivo and in vitro studies', Toxicology and Applied Pharmacology, vol. 417, p. 115441. https://doi.org/10.1016/j.taap.2020.115441.
Purushottam, B. dan Reddy, R. A. (2024) 'Cadmium Toxicity: Sources, Mechanisms and Human Health Implications: A Comprehensive Review', UTTAR PRADESH JOURNAL OF ZOOLOGY, vol. 45, no. 15, pp. 442–450. https://doi.org/10.56557/upjoz/2024/v45i154260.
Putra, A. P., Rahayu, T. dan Surbakti, I. (2021) 'Paparan logam berat terhadap kualitas sperma pada hewan coba', Jurnal Biomedis dan Kesehatan, vol. 18, no. 2, pp. 112–118.
Rohmawati, Y. dan Kuntjoro, S. (2021) 'Studi Kadar Logam Berat Kadmium (Cd) Pada Tumbuhan Air di Sungai Buntung Sidoarjo', LenteraBio: Berkala Ilmiah Biologi, vol. 10, no. 1, pp. 86–93.
Roosmini, D., Wardhani, E. dan Notodarmojo, S. (2022) 'Risk Assessment and Fractionation of Cadmium Contamination in Sediment of Saguling Lake in West Java Indonesia', Journal of Engineering and Technological Sciences, vol. 54, no. 2, p. 220203. https://doi.org/10.5614/j.eng.technol.sci.2022.54.2.3
Ruczaj, A. dan Brzóska, M. M. (2023) 'Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data', Journal of Applied Toxicology, vol. 43, no. 1, pp. 66–88. https://doi.org/10.1002/jat.4322
Saengwilai, P., & Meeinkuirt, W. (2021). Cadmium (Cd) and zinc (Zn) accumulation by Thai rice varieties and health risk assessment in a Cd–Zn co-contaminated paddy field: effect of soil amendments. Environmental Geochemistry and Health, 43(9), 3659-3674.
Saputra, D. R. dan Hastuti, D. T. (2019) 'Arsenik sebagai disrupter endokrin dan dampaknya pada sistem reproduksi wanita', Jurnal Gizi dan Reproduksi, vol. 10, no. 1, pp. 23–30.
Sharma, R. K., Agrawal, M. dan Marshall, F. M. (2007) 'Heavy metals contamination of soil and vegetables in suburban areas of Varanasi, India', Ecotoxicology and Environmental Safety, vol. 66, pp. 258–266.
Suhani, I., Sahab, S., Srivastava, V., & Singh, R. P. (2021). Impact of cadmium pollution on food safety and human health. Current opinion in toxicology, 27, 1-7.
Suwatvitayakorn, P. et al. (2020) 'Human health risk assessment of cadmium exposure through rice consumption in cadmium-contaminated areas of the Mae Tao sub-district, Tak, Thailand', Environmental Geochemistry and Health, vol. 42, no. 8, pp. 2331–2344. https://doi.org/10.1007/s10653-019-00410-7
Syeda, T. dan Cannon, J. R. (2021) 'Environmental exposures and the etiopathogenesis of Alzheimer's disease: the potential role of BACE1 as a critical neurotoxic target', Journal of Biochemical and Molecular Toxicology, vol. 35, no. 4, p. e22694. https://doi.org/10.1002/jbt.22694
Tasin, F. R., Ahmed, A., Halder, D., & Mandal, C. (2022). On‐going consequences of in utero exposure of Pb: An epigenetic perspective. Journal of Applied Toxicology, 42(10), 1553-1569.
Tsadilas, C. D. et al. (2005) 'Cadmium uptake by tobacco as affected by liming, N-form, and year of cultivation', Environmental Pollution, vol. 134, pp. 239–246.
Tun, A. Z., Wongsasuluk, P. dan Siriwong, W. (2020) 'Heavy Metals in the Soils of Placer Small-Scale Gold Mining Sites in Myanmar', Journal of Health and Pollution, vol. 10, no. 27, p. 200911. https://doi.org/10.5696/2156-9614-10.27.200911
Vongdala, N. et al. (2018) 'Heavy Metal Accumulation in Water, Soil, and Plants of Municipal Solid Waste Landfill in Vientiane, Laos', International Journal of Environmental Research and Public Health, vol. 16, no. 1, p. 22. https://doi.org/10.3390/ijerph16010022
Wang, B. dan Du, Y. (2013) 'Cadmium and its neurotoxic effects', Oxidative Medicine and Cellular Longevity, vol. 2013, p. 898034. 10.1155/2013/898034
Win-Thu, M. et al. (2021) 'Environmental cadmium exposure induces kidney tubular and glomerular dysfunction in the Myanmar adults', The Journal of Toxicological Sciences, vol. 46, no. 7, pp. 319–328. https://doi.org/10.2131/jts.46.319
Yang, Y. et al. (2023) 'Effects of cadmium pollution on human health: A narrative review', Toxics, vol. 11, no. 4, p. 327. https://doi.org/10.3390/toxics11040327
Yang, Y., Hassan, M. F., Ali, W., Zou, H., Liu, Z. dan Ma, Y. (2025) 'Dampak Polusi Kadmium terhadap Kesehatan Manusia: Sebuah Tinjauan Naratif', Suasana, vol. 16, no. 225. https://doi.org/10.3390/atmos16020225
Yin, S. et al. (2022) 'Cadmium exposure and reproductive health: A systematic review of epidemiological and experimental evidence', Ecotoxicology and Environmental Safety, vol. 241, p. 113786. https://doi.org/10.1016/j.ecoenv.2022.113786.
Yang, Y. et al. (2025) 'Effects of Cadmium Pollution on Human Health: A Narrative Review', Atmosfera, vol. 16, no. 225. https://doi.org/10.3390/atmos16020225
Zhao, M. et al. (2020) 'Cadmium induces reproductive toxicity by disrupting the hypothalamus–pituitary–gonadal axis and reducing testosterone synthesis in male rats', Ecotoxicology and Environmental Safety, vol. 200, p. 110732. . https://doi.org/10.1016/j.ecoenv.2020.110732.
Zhao, D., Wang, P., & Zhao, F. J. (2023). Dietary cadmium exposure, risks to human health and mitigation strategies. Critical reviews in environmental science and technology, 53(8), 939-963.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Indonesian Journal of Global Health Research

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.







