Analysis of Factors Influencing Ankle-Brachial Index Values in Patients with Diabetes Mellitus

Authors

  • Achmad Syukkur STIKes Panti Waluya Malang
  • Emy Sutiyarsih STIKes Panti Waluya Malang

DOI:

https://doi.org/10.37287/ijghr.v8i2.610

Keywords:

ABI, diabetes mellitus, PAD

Abstract

Peripheral artery disease (PAD) is one of the chronic complications that frequently occurs in patients with diabetes mellitus (DM). PAD can be detected early using the non-invasive Ankle-Brachial Index (ABI) method. An abnormal ABI value may indicate impaired peripheral blood flow and serves as an important indicator of the risk of amputation and cardiovascular morbidity. The aim of this study was to analyze the factors affecting ABI values in patients with DM, namely age, sex, Body Mass Index (BMI), duration of DM, smoking status, physical activity, foot care status, history of DM complications, adherence to DM therapy, and blood glucose levels. This research employed a quantitative descriptive non-experimental approach with a cross-sectional design. The sample was obtained through accidental sampling, resulting in 106 respondents. Data were analyzed using the Spearman’s rho correlation test. The findings revealed that factors significantly associated with ABI values included duration of DM (p = 0.000), smoking status (p = 0.029), foot care status (p = 0.000), history of DM complications (p = 0.000), adherence to DM therapy (p = 0.000), and blood glucose levels (p = 0.000). The results of this study are expected to encourage respondents, particularly DM patients, to improve their overall adherence to diabetes therapy.

References

Adam, M., & Isytiaroh, I. (2021). Penerapan Perawatan Kaki untuk Meningkatkan Sirkulasi Darah pada Penderita Diabetes Melitus Tipe 2. Prosiding Seminar Nasional Kesehatan, 1, 1727–1731. https://doi.org/10.48144/prosiding.v1i.923

Allison, M. A., Armstrong, D. G., Goodney, P. P., Hamburg, N. M., Kirksey, L., Lancaster, K. J., Mena-Hurtado, C. I., Misra, S., Treat-Jacobson, D. J., Solaru, K. T. W., on behalf of the American Heart Association Council on Peripheral Vascular Disease; Council on Hypertension;, on Lifestyle, C., & Health, C. (2023). Health Disparities in Peripheral Artery Disease: A Scientific Statement From the American Heart Association. Circulation, 148(3), 286–296. https://doi.org/10.1161/CIR.0000000000001153

Alves-Cabratosa, L., Comas-Cufí, M., Ponjoan, A., Garcia-Gil, M., Martí-Lluch, R., Blanch, J., Elosua-Bayes, M., Parramon, D., Camós, L., Guzmán, L., & Ramos, R. (2020). Levels of Ankle-Brachial Index and The Risk of Diabetes Mellitus Complications. BMJ Open Diabetes Research & Care, 8(1). https://doi.org/10.1136/bmjdrc-2019-000977

Bechara, N., Hng, T.-M., & Gunton, J. E. (2024). The aAssociation between Tobacco Smoking and Systolic Toe Pressures in Active Foot Ulceration. Scientific Reports, 14(1), 8550. https://doi.org/10.1038/s41598-024-59158-5

Fadlilah, S., Nurrahma, H. A., Sumarni, S., Tsai, J. R., Wang, W.-J., & Tsai, H. T. (2025). Relationships and Synergistic Effects of Body Mass Index and Blood Glucose Marker on the Ankle-Brachial Index in Adult With Type 2 Diabetes Mellitus: A Cross-Sectional Study. Nursing & Health Sciences, 27(1), e70055. https://doi.org/10.1111/nhs.70055

Gerhard-Herman, M. D., Gornik, H. L., Barrett, C., Barshes, N. R., Corriere, M. A., Drachman, D. E., Fleisher, L. A., Fowkes, F. G. R., Hamburg, N. M., Kinlay, S., Lookstein, R., Misra, S., Mureebe, L., Olin, J. W., Patel, R. A. G., Regensteiner, J. G., Schanzer, A., Shishehbor, M. H., Stewart, K. J., … Walsh, M. E. (2017). 2016 AHA/ACC Guideline on The Management of Patients With Lower Extremity Peripheral Artery Disease. JACC, 69(11), e71–e126. https://doi.org/10.1016/j.jacc.2016.11.007

Heffron, S. P., Dwivedi, A., Rockman, C. B., Xia, Y., Guo, Y., Zhong, J., & Berger, J. S. (2020). Body Mass Index and Peripheral Artery Disease. Physiology & Behavior, 176(1), 100–106. https://doi.org/10.1177/0022146515594631.Marriage

Heidari, S., Yekefallah, L., Jalalpor, A., Ranjbaran, M., & Talakoob, H. (2021). Relationship Between Medication Adherence and Ankle-Brachial Index Value in Patients With Hypertension. Journal of Inflammatory Diseases, 25(3). https://brieflands.com/articles/jid-156291.bib

Huether, S. E., McCance, K. L., Brashers, V. L., & Rote, N. S. (2019). Buku Ajar Patofisiologi (D. S. Wahono, R. Ratnawati, & H. Sujuti (eds.); 6th ed.). Elsevier.

IDF. (2023). Diabetes Facts and Figures. International Diabetes Federation. https://idf.org/about-diabetes/diabetes-facts-figures/

Kristina, S., Putri, L., Riani, D., Ikawati, Z., & Endarti, D. (2019). VALIDITY OF SELF-REPORTED MEASURE OF MEDICATION ADHERENCE AMONG DIABETIC PATIENTS IN INDONESIA. International Research Journal of Pharmacy, 10, 144–148. https://doi.org/10.7897/2230-8407.1007234

McDermott, M. M., Liu, K., Criqui, M. H., Ruth, K., Goff, D., Saad, M. F., Wu, C., Homma, S., & Sharrett, A. R. (2005). Ankle-Brachial Index and Subclinical Cardiac and Carotid Disease: The Multi-Ethnic Study of Atherosclerosis. American Journal of Epidemiology, 162(1), 33–41. https://doi.org/10.1093/aje/kwi167

Shu, J., & Santulli, G. (2018). Update on Peripheral Artery Disease: Epidemiology and Evidence-based Facts. Atherosclerosis, 275, 379–381. https://doi.org/https://doi.org/10.1016/j.atherosclerosis.2018.05.033

Smeltzer, S. C., Bare, B. G., Hinkle, J. L., & Cheever, kerry H. (2015). Medical Surgical Nursing (12th ed.). Lippincott Williams & Wilkins.

Sommers, M. S. (2018). Disesases & Disorders : A Nursing Therapeutics Manual (6th ed.). F.A. Davus Company.

Song, P., Rudan, D., Zhu, Y., Fowkes, F. J. I., Rahimi, K., Fowkes, F. G. R., & Rudan, I. (2019). Global, Regional, and National Prevalence and Risk Factors for Peripheral Artery Disease in 2015: An Updated Systematic Review and Analysis. The Lancet Global Health, 7(8), e1020–e1030. https://doi.org/10.1016/S2214-109X(19)30255-4

Wilcox, T., Newman, J. D., Maldonado, T. S., Rockman, C., & Berger, J. S. (2018). Peripheral Vascular Disease Risk in Diabetic Individuals Without Coronary Heart Disease. Atherosclerosis, 275, 419–425. https://doi.org/https://doi.org/10.1016/j.atherosclerosis.2018.04.026

Yang, M.-C., Huang, Y.-Y., Hsieh, S.-H., Sun, J.-H., Wang, C.-C., & Lin, C.-H. (2021). Ankle-Brachial Index Is Independently Associated With Cardiovascular Outcomes and Foot Ulcers in Asian Patients With Type 2 Diabetes Mellitus. Frontiers in Endocrinology, 12, 752995. https://doi.org/10.3389/fendo.2021.752995

Downloads

Published

2026-03-08

How to Cite

Syukkur, A., & Sutiyarsih, E. (2026). Analysis of Factors Influencing Ankle-Brachial Index Values in Patients with Diabetes Mellitus. Indonesian Journal of Global Health Research, 8(2), 535–542. https://doi.org/10.37287/ijghr.v8i2.610

Similar Articles

<< < 1 2 3 4 

You may also start an advanced similarity search for this article.